SCHEMBL16638748

SCHEMBL16638748

CCO[Si](CCCNCCP(=O)(OCC)OCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.43
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
TSHR P16473 1/20 0.35
SAT1 P21673 1/20 0.35
S1PR2 O95136 5/20 0.34
S1PR4 O95977 5/20 0.34
S1PR1 P21453 5/20 0.34
S1PR3 Q99500 5/20 0.34
S1PR5 Q9H228 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
PLAU P00749 1/20 0.32
FPR2 P25090 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596887 0.83 S1PR2 (0.47) CA12CA1CA2CA9SAT1
SCHEMBL14768680 0.83 PPARD (0.46) PPARDCA12CA1CA2CA9
SCHEMBL3680110 0.83 PPARD (0.47) PPARDCA12CA1CA2CA9
SCHEMBL2596914 0.82 S1PR2 (0.46) CA12CA1CA2CA9SAT1
SCHEMBL57190 0.80 CYP2C19 (0.38) TSHRMEN1CYP2C19KMT2A
SCHEMBL491800 0.80 PPARD (0.62) PPARDCA12CA1CA2CA9
SCHEMBL10612816 0.80 PPARD (0.44) PPARDTSHR
SCHEMBL16638746 0.79 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL3341956 0.79 PPARD (0.52) PPARDCA12CA1CA2CA9
SCHEMBL2232173 0.79 PPARD (0.50) PPARDCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827807-B2 Metal surface coatings for improving bond performance and methods of making the same NOVELIS INC. (US) 2023-11-28 US disclosed
US-11827807-B2 Metal surface coatings for improving bond performance and methods of making the same NOVELIS INC. (US) 2023-11-28 US disclosed
US-11827807-B2 Metal surface coatings for improving bond performance and methods of making the same NOVELIS INC. (US) 2023-11-28 US disclosed
EP-3997180-B1 METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME NOVELIS INC (US) 2023-08-30 EP disclosed
EP-3997180-B1 METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME NOVELIS INC (US) 2023-08-30 EP disclosed
US-20220340763-A1 METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME NOVELIS INC. (US) 2022-10-27 US disclosed
EP-3997180-A1 METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME Novelis Inc. (US) 2022-05-18 EP disclosed
US-9006372-B2 Silicone resins and their use in polymer compositions DOW CORNING (SHANGHAI) CO LTD (CN) 2015-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827807-B2 Metal surface coatings for improving bond performance and methods of making the same SOD1, AEBP2, ITGA8 PPARD 4800/4885CA12 324/4885CA1 56/4885
US-20220340763-A1 METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME SOD1, AEBP2, ITGA8 PPARD 4800/4885CA12 324/4885CA1 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.