Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.76 |
| ▸ | FAP | Q12884 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070860 | 0.90 | CYP3A4 (0.77) | CYP3A4FAPCYP2D6 | |
| SCHEMBL7267656 | 0.89 | CYP3A4 (0.76) | CYP3A4FAPCYP2D6 | |
| SCHEMBL7268779 | 0.89 | CYP3A4 (0.76) | CYP3A4FAPCYP2D6 | |
| SCHEMBL13983477 | 0.89 | CYP3A4 (0.76) | CYP3A4FAPCYP2D6 | |
| SCHEMBL24809663 | 0.88 | CYP3A4 (0.74) | CYP3A4FAPCYP2D6 | |
| SCHEMBL1393451 | 0.88 | CYP3A4 (0.74) | CYP3A4FAPCYP2D6 | |
| SCHEMBL1393452 | 0.88 | CYP3A4 (0.74) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28928317 | 0.87 | CYP3A4 (0.72) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28928318 | 0.87 | CYP3A4 (0.72) | CYP3A4FAPCYP2D6 | |
| Tenofovir Anhydrous SCHEMBL2040329 | 0.86 | CYP3A4 (1.00) | CYP3A4FAPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860185-A1 | An improved process for the preparation of Tenofovir disoproxil and pharmaceutically acceptable salts thereof | Zentiva, k.s. (CZ) | 2015-04-15 | — | — | EP | disclosed |