Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934472 | 0.93 | MAOB (0.53) | MAOBL3MBTL1LMNAGAAKMT2A | |
| SCHEMBL4545481 | 0.92 | MAOB (0.46) | MAOBL3MBTL1LMNAGAAKMT2A | |
| SCHEMBL15934631 | 0.91 | MAOB (0.51) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL17852726 | 0.90 | MAOB (0.47) | MAOBL3MBTL1LMNAGAAKMT2A | |
| SCHEMBL19220605 | 0.88 | LMNA (0.49) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL15934730 | 0.88 | MAPT (0.48) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL18854360 | 0.87 | MAOB (0.50) | MAOBL3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL19334690 | 0.87 | MAOB (0.52) | MAOBL3MBTL1LMNAGAAKMT2A | |
| SCHEMBL4545480 | 0.87 | MAOB (0.45) | MAOBL3MBTL1LMNAGAAKMT2A | |
| SCHEMBL10188415 | 0.87 | MAOB (0.46) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540720-B1 | 1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE DERIVATIVE AND USE OF SAME AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2015-04-15 | — | — | EP | disclosed |