Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.46 |
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774850 | 0.95 | PLA2G2C (0.49) | PLA2G2CCTSKCTSS | |
| SCHEMBL24485595 | 0.90 | PLA2G2C (0.57) | PLA2G2CCTSKCTSS | |
| SCHEMBL2836699 | 0.90 | PLA2G2C (0.57) | PLA2G2CCTSKCTSS | |
| SCHEMBL13942942 | 0.88 | PLA2G2C (0.48) | PLA2G2CCTSKCTSS | |
| SCHEMBL8298404 | 0.88 | PLA2G2C (0.48) | PLA2G2CCTSKCTSS | |
| SCHEMBL19014799 | 0.87 | CTSK (0.47) | PLA2G2CCTSKCTSS | |
| SCHEMBL3389057 | 0.86 | CA1 (0.49) | CTSKCTSSSYK | |
| SCHEMBL12629370 | 0.83 | PLA2G2C (0.62) | PLA2G2CCTSKCTSS | |
| SCHEMBL15289799 | 0.81 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL20170528 | 0.81 | CTSK (0.49) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540720-B1 | 1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE DERIVATIVE AND USE OF SAME AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2015-04-15 | — | — | EP | disclosed |