Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670577 | 0.84 | CYP1A2 (0.50) | LTA4HEPHX2ALOX5PTGESCYP1A2 | |
| SCHEMBL9538995 | 0.82 | CYP1A2 (0.61) | ALOX5PTGESCYP1A2KDM4ENPC1 | |
| SCHEMBL16414559 | 0.78 | IGF1R (0.46) | LTA4HEPHX2ALOX5PTGESCYP1A2 | |
| SCHEMBL15802596 | 0.77 | CYP1A2 (0.59) | ALOX5PTGESCYP1A2KDM4ENPC1 | |
| SCHEMBL81147 | 0.77 | CYP1A2 (0.62) | LTA4HEPHX2CYP1A2SIGMAR1HDAC1 | |
| SCHEMBL31265269 | 0.77 | CYP1A2 (0.62) | LTA4HEPHX2CYP1A2SIGMAR1HDAC1 | |
| SCHEMBL16170703 | 0.74 | CYP2A6 (0.50) | LTA4HEPHX2ALOX5PTGESCYP1A2 | |
| SCHEMBL5855257 | 0.74 | CYP2A6 (0.43) | LTA4HEPHX2ALOX5PTGESCYP1A2 | |
| SCHEMBL9716439 | 0.74 | CYP3A4 (0.50) | KDM4ELMNATP53CYP3A4SLC6A2 | |
| SCHEMBL16414413 | 0.74 | SLC6A2 (0.47) | LTA4HEPHX2ALOX5PTGESCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860169-A2 | Method for obtaining novel derivatives of naphtalene for the in vivo diagnosis of Alzheimer's disease | Centro De Neurociencias De Cuba (CU) | 2015-04-15 | — | — | EP | disclosed |