Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15802596 | 0.95 | CYP1A2 (0.59) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL2663510 | 0.89 | CYP1A2 (0.65) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL17256182 | 0.86 | CYP1A2 (0.61) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL9670577 | 0.84 | CYP1A2 (0.50) | CYP1A2KDM4EMAPTALOX5PTGES | |
| SCHEMBL11246667 | 0.84 | CYP1A2 (0.58) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL79113 | 0.83 | CALM1 (0.68) | ALOX5IGF1RALOX15CALM1CYP4A11 | |
| SCHEMBL16638878 | 0.82 | LTA4H (0.44) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL890459 | 0.82 | CYP1A2 (0.57) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL7061128 | 0.82 | PTGS2 (0.57) | CYP1A2KDM4ENPC1LMNATP53 | |
| SCHEMBL2666094 | 0.81 | PTGS1 (0.62) | CYP1A2KDM4ENPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537313-A1 | ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY. | GENTILI IST SPA (IT) | 1993-04-21 | — | — | EP | disclosed |
| WO-1992019584-A1 | ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY | ISTITUTO GENTILI S.P.A. (IT) | 1992-11-12 | — | — | WO | disclosed |
| EP-0314759-A4 | ASYMMETRIC HYDROFORMYLATIONS OF PROCHIRAL OLEFINS TO CHIRAL ALDEHYDES IN HIGH ENANTIOMERIC EXCESS. | UNIV COLORADO STATE RES FOUND (US) | 1990-01-29 | — | — | EP | disclosed |
| EP-0314759-A1 | ASYMMETRIC HYDROFORMYLATIONS OF PROCHIRAL OLEFINS TO CHIRAL ALDEHYDES IN HIGH ENANTIOMERIC EXCESS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1989-05-10 | — | — | EP | disclosed |
| WO-1988008835-A1 | ASYMMETRIC HYDROFORMYLATIONS OF PROCHIRAL OLEFINS TO CHIRAL ALDEHYDES IN HIGH ENANTIOMERIC EXCESS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1988-11-17 | — | — | WO | disclosed |