Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344902 | 0.79 | PRSS1 (0.44) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 | |
| SCHEMBL8410463 | 0.77 | PRSS1 (0.54) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 | |
| SCHEMBL2658791 | 0.75 | CES2 (0.58) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 | |
| SCHEMBL19518885 | 0.75 | RAD52 (0.39) | MAPTLMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL10267005 | 0.75 | TDP1 (0.54) | MAPTLMNAGAASMN1; SMN2CES2 | |
| SCHEMBL31484336 | 0.75 | PRSS1 (0.52) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 | |
| SCHEMBL12824890 | 0.75 | PRSS1 (0.64) | PRSS1PRSS2PRSS3MAPTLMNA | |
| SCHEMBL902913 | 0.75 | PRSS1 (0.52) | PRSS1PRSS2PRSS3MAPTLMNA | |
| SCHEMBL1363337 | 0.75 | PRSS1 (0.52) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 | |
| SCHEMBL23476007 | 0.74 | PRSS1 (0.47) | PRSS1PRSS2PRSS3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860176-A1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | Beijing Foreland Biopharma Co., Ltd. (CN) | 2015-04-15 | — | — | EP | disclosed |