Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 1.00 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morin Pentaethyl Ether SCHEMBL1664234 | 0.91 | ADORA3 (1.00) | ADORA3ACE2ABCG2ABCB1POLH | |
| SCHEMBL30741225 | 0.83 | ADORA3 (1.00) | ADORA3ACE2SLC22A2SLC22A1PPARG | |
| SCHEMBL1663784 | 0.83 | ADORA3 (1.00) | ADORA3ACE2SLC22A2SLC22A1PPARG | |
| SCHEMBL31513992 | 0.82 | ACE2 (0.81) | ADORA3ACE2ABCG2ABCB1ELANE | |
| SCHEMBL23278851 | 0.79 | ADORA3 (0.65) | ADORA3ACE2ABCG2ABCB1ELANE | |
| SCHEMBL16160540 | 0.75 | ADORA3 (0.61) | ADORA3ACE2ABCG2ABCB1ELANE | |
| SCHEMBL6331623 | 0.72 | ADORA3 (0.63) | ADORA3ACE2ABCG2ABCB1SLC22A2 | |
| SCHEMBL16160537 | 0.72 | ADORA3 (0.77) | ADORA3ACE2ELANESLC22A2SLC22A1 | |
| SCHEMBL1664225 | 0.71 | ABCG2 (1.00) | ADORA3ABCG2ABCB1SLC22A2SLC22A1 | |
| SCHEMBL20630735 | 0.71 | ADORA3 (0.69) | ADORA3ACE2ELANEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311806-A2 | Dihydropyridine-, pyridine-, benzopyranone- and triazoloquinazoline derivatives, their preparation and their use as adenosine receptor antagonists | The United States of America, Represented by the Secretary, Department of Health and Human Services (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-1051505-A1 | PROCESS OF EXTRACTING TAXOL FROM TAXUS CUSPIDATA | Han, Man Woo (KR) | 2000-11-15 | — | — | EP | disclosed |
| US-6066642-A | FOR SELECTIVELY BLOCKING THE A3 ADENOSINE RECEPTOR OF A MAMMAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-05-23 | — | — | US | disclosed |
| WO-1999037796-A1 | PROCESS OF EXTRACTING TAXOL FROM TAXUS CUSPIDATA | HAN MAN WOO (KR) | 1999-07-29 | — | — | WO | disclosed |