Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938902 | 0.88 | HDAC4 (0.32) | POLB | |
| SCHEMBL8002864 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL1645088 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL1683122 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL8005984 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL3792590 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL1683120 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL13059221 | 0.86 | ADRB3 (0.36) | — | |
| SCHEMBL11975940 | 0.85 | HDAC4 (0.33) | POLB | |
| SCHEMBL8249373 | 0.84 | DPP4 (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364310-B1 | 4-AMINO-4-OXOBUTANOYL PEPTIDE CYCLIC ANALOGUES, INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-2374812-B1 | 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication | ACHILLION PHARMACEUTICALS INC (US) | 2015-04-15 | — | — | EP | disclosed |