SCHEMBL16639218

SCHEMBL16639218

CC(I)NC(=O)c1cc(Br)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.39
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
CAPN1 P07384 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
F10 P00742 1/20 0.31
MALT1 Q9UDY8 2/20 0.31
PDE4A P27815 1/20 0.30
KCNH2 Q12809 1/20 0.30
PIK3CD O00329 1/20 0.30
PIK3R1 P27986 1/20 0.30
PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16622527 0.93 DHODH (0.34) DHODHMEN1KMT2ALMNACAPN1
SCHEMBL10028777 0.93 DHODH (0.40) DHODHMEN1KMT2ALMNACAPN1
SCHEMBL16639217 0.92 DHODH (0.42) DHODHLMNAS1PR1S1PR3F10
SCHEMBL18117830 0.90 DHODH (0.38) DHODHMEN1KMT2ALMNACAPN1
SCHEMBL16622508 0.89 PDE4B (0.35) DHODHMEN1KMT2A
SCHEMBL16622520 0.89 DHODH (0.40) DHODHKMT2ACAPN1S1PR1S1PR3
SCHEMBL10028778 0.88 DHODH (0.41) DHODHMEN1KMT2ALMNAMALT1
SCHEMBL16622530 0.87 DHODH (0.42) DHODHS1PR1S1PR3F10MALT1
SCHEMBL951319 0.87 DHODH (0.40) DHODHMEN1KMT2ALMNAMALT1
SCHEMBL16622522 0.86 DHODH (0.43) DHODHKMT2AS1PR1S1PR3MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699290-B2 INSECTICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING ANTHRANILIC ACID AMIDES AND AT LEAST ONE OTHER INSECTICIDE BAYER CROPSCIENCE AG (DE) 2015-04-15 EP disclosed