SCHEMBL16639217

SCHEMBL16639217

Cc1cc(Br)cc(C(=O)NC(C)I)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.42
MALT1 Q9UDY8 1/20 0.33
LMNA P02545 1/20 0.33
SORT1 Q99523 1/20 0.32
MAPT P10636 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
PDE4A P27815 2/20 0.31
F10 P00742 1/20 0.30
GCK P35557 2/20 0.30
KCNH2 Q12809 2/20 0.30
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16622530 0.93 DHODH (0.42) DHODHMALT1S1PR1S1PR3PDE4A
SCHEMBL782222 0.93 DHODH (0.43) DHODHMALT1LMNASORT1MAPT
SCHEMBL16622522 0.92 DHODH (0.43) DHODHMALT1S1PR1S1PR3PDE4A
SCHEMBL16639218 0.92 DHODH (0.39) DHODHMALT1LMNAS1PR1S1PR3
SCHEMBL16639211 0.90 DHODH (0.35) DHODHMAPTF10
SCHEMBL30058805 0.89 DHODH (0.44) DHODHMALT1LMNASORT1MAPT
SCHEMBL782370 0.89 DHODH (0.44) DHODHMALT1LMNASORT1MAPT
SCHEMBL16622520 0.88 DHODH (0.40) DHODHMALT1S1PR1S1PR3GCK
SCHEMBL28533596 0.87 DHODH (0.39) DHODHMALT1LMNAS1PR1S1PR3
SCHEMBL10028768 0.86 DHODH (0.43) DHODHMALT1LMNAMAPTS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699290-B2 INSECTICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING ANTHRANILIC ACID AMIDES AND AT LEAST ONE OTHER INSECTICIDE BAYER CROPSCIENCE AG (DE) 2015-04-15 EP disclosed