SCHEMBL16639225

SCHEMBL16639225

c1ccc2c(c1)oc1ccc(-n3c4ccc(-c5cccc6c5oc5ccccc56)cc4c4cc(-c5cccc6c5oc5ccccc56)ccc43)cc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
PRKDC P78527 5/20 0.43
GGPS1 O95749 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.38
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
ALDH1A1 P00352 3/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
ATM Q13315 1/20 0.36
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15630643 0.99 ALOX5 (0.52) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17248353 0.98 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL20715118 0.98 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL22107631 0.95 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL21946606 0.95 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17885403 0.94 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL22672208 0.93 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL18266066 0.93 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15630642 0.93 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL12158853 0.93 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861044-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE JOLED INC (JP) 2019-03-27 EP disclosed
US-9257663-B2 Organic electroluminescent element and display device SONY CORPORATION (JP) 2016-02-09 US disclosed
US-20150171356-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-06-18 US disclosed
US-20150171356-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-06-18 US disclosed
EP-2861044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE Sony Corporation (JP) 2015-04-15 EP disclosed