SCHEMBL16639308

SCHEMBL16639308

Cc1ccc(N(c2ccc(-c3cc(C(C)C)c4ccc5c(N(c6ccccc6-c6ccccc6)c6cccc7c6oc6ccccc67)cc(C(C)C)c6ccc3c4c65)cc2)c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.33
ALOX5 P09917 1/20 0.32
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639640 0.96 ALOX5 (0.33) ALOX5
SCHEMBL16639319 0.93 ALOX5 (0.34) ALOX5
SCHEMBL16639343 0.91 ALOX5 (0.35) ALOX5TNKSPARP1TNKS2PARP2
SCHEMBL16639334 0.91 ALOX5 (0.36) ALOX5TNKSPARP1TNKS2PARP2
SCHEMBL27055798 0.91 MAOB (0.37) MAOBALOX5TNKSPARP1TNKS2
SCHEMBL22489288 0.90 MAOB (0.33) MAOBALOX5TNKSPARP1TNKS2
SCHEMBL24872562 0.89
SCHEMBL4079924 0.89 ALOX5 (0.36) ALOX5TNKSPARP1TNKS2PARP2
SCHEMBL16639315 0.89 MAOB (0.33) MAOBTNKSPARP1TNKS2PARP2
SCHEMBL22489395 0.88 MAOB (0.33) MAOBALOX5TNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed