SCHEMBL16639311

SCHEMBL16639311

c1ccc(-c2ccc(N(c3ccc(-c4ccc5ccc6c(-c7ccc(N(c8ccc(-c9ccccc9)cc8-c8ccccc8)c8cccc9c8oc8ccccc89)cc7)ccc7ccc4c5c76)cc3)c3cccc4c3oc3ccccc34)c(-c3ccccc3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
PGR P06401 2/20 0.31
NR3C1 P04150 1/20 0.30
AR P10275 1/20 0.30
CYP17A1 P05093 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639333 0.98 ALOX5 (0.36) ALOX5CDC14BCDC14APLA2G2APLA2G4A
SCHEMBL16639612 0.96 ALOX5 (0.33) ALOX5CDC14BCDC14A
SCHEMBL16641956 0.93 ALOX5 (0.39) ALOX5CDC14BCDC14APLA2G2APLA2G4A
SCHEMBL22433797 0.92 ALOX5 (0.35) ALOX5CDC14BCDC14A
SCHEMBL16639325 0.92 MAOB (0.31) ALOX5
SCHEMBL16639331 0.92 ALOX5 (0.38) ALOX5CDC14BCDC14ACYP17A1CYP19A1
SCHEMBL22435724 0.90 ALOX5 (0.41) ALOX5CDC14BCDC14APLA2G2APLA2G4A
SCHEMBL16639610 0.90 ALOX5 (0.34) ALOX5CDC14BCDC14A
SCHEMBL4083880 0.89 ALOX5 (0.38) ALOX5CDC14BCDC14APLA2G2APLA2G4A
SCHEMBL18798598 0.89 ALOX5 (0.38) ALOX5CDC14BCDC14APLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed