Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196800 | 0.91 | TNF (0.40) | TNFPTGDR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL18191988 | 0.90 | TNF (0.38) | TNFPTGDR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL16639306 | 0.90 | CYP11B1 (0.37) | TNFPTGDR2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL16639278 | 0.89 | RXRA (0.31) | TNFALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL16639279 | 0.89 | RXRA (0.31) | TNFALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL18382438 | 0.88 | CYP11B1 (0.41) | TNFCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL18382337 | 0.88 | CYP11B1 (0.41) | TNFCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL18382339 | 0.87 | CYP11B1 (0.39) | TNFPTGDR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL16639338 | 0.86 | RXRA (0.31) | TNFMAPTNPC1LMNAHTT | |
| SCHEMBL16639634 | 0.86 | RXRA (0.31) | TNFMAPTNPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |