Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640196 | 0.90 | TSHR (0.51) | TSHRHPGDLPAR1LPAR2ENPP2 | |
| SCHEMBL16640032 | 0.88 | TSHR (0.60) | TSHRHPGDHTTSMN1; SMN2LPAR1 | |
| SCHEMBL21204352 | 0.87 | LPAR1 (0.55) | TSHRLPAR1LPAR2ENPP2CASP2 | |
| SCHEMBL19931551 | 0.87 | TSHR (0.47) | TSHRHPGDSMN1; SMN2LPAR1LPAR2 | |
| SCHEMBL16639380 | 0.87 | LPAR1 (0.55) | TSHRLPAR1LPAR2ENPP2CASP2 | |
| SCHEMBL23451136 | 0.87 | TSHR (0.47) | TSHRHPGDHTTSMN1; SMN2LPAR1 | |
| SCHEMBL24429214 | 0.87 | LPAR1 (0.55) | TSHRLPAR1LPAR2ENPP2CASP2 | |
| SCHEMBL21204263 | 0.87 | LPAR1 (0.55) | TSHRLPAR1LPAR2ENPP2CASP2 | |
| SCHEMBL21204364 | 0.87 | LPAR1 (0.55) | TSHRLPAR1LPAR2ENPP2CASP2 | |
| SCHEMBL21204363 | 0.87 | CASP2 (0.56) | TSHRLPAR1LPAR2ENPP2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663784-B2 | Single-stranded nucleic acid molecule for regulating expression of gene having delivering function | BONAC CORPORATION (JP) | 2017-05-30 | — | — | US | disclosed |
| US-20150105443-A1 | SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR REGULATING EXPRESSION OF GENE HAVING DELIVERING FUNCTION | BONAC CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |