Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639635 | 1.00 | HSD17B1 (0.35) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639281 | 0.99 | HSD17B1 (0.35) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639276 | 0.99 | HSD17B1 (0.35) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639321 | 0.96 | HSD17B1 (0.33) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16641969 | 0.96 | HSD17B1 (0.36) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639323 | 0.96 | HSD17B1 (0.33) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639295 | 0.94 | HSD17B1 (0.35) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639280 | 0.94 | HPRT1 (0.37) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639275 | 0.94 | HPRT1 (0.37) | HSD17B1HSD17B2MEN1APAF1NPC1 | |
| SCHEMBL16639310 | 0.90 | HSD17B1 (0.33) | HSD17B1HSD17B2MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |