Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775431 | 1.00 | KDM4E (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL12764437 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL14777035 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL12764455 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL23658042 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL23658041 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL12764438 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL24772917 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL14787899 | 0.94 | MAPT (0.53) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 | |
| SCHEMBL81382 | 0.87 | ALDH1A1 (0.64) | KDM4EDYRK1ADYRK2DYRK1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9786941-B2 | Metal ionophores in PEM membranes | GM Global Technology Operations LLC (US) | 2017-10-10 | — | — | US | disclosed |
| US-20150105239-A1 | CROWN ETHER CONTAINING PEM ELECTRODE | GM GLOBAL TECH OPERATIONS INC (US) | 2015-04-16 | — | — | US | disclosed |