Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192015 | 0.76 | CTSK (0.70) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL6311475 | 0.76 | CTSK (0.70) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL6782182 | 0.76 | CTSK (0.70) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL1663997 | 0.75 | NPC1 (0.47) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL1663903 | 0.74 | CTSK (0.45) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL1663905 | 0.74 | CTSK (0.45) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL1643093 | 0.73 | CTSK (0.66) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL1059174 | 0.73 | CTSK (0.66) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL5325864 | 0.73 | CTSK (0.66) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10658290 | 0.72 | CTSK (0.59) | CTSKCTSLCTSBCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305652-A2 | Trisubstituted quinazolinone derivatives as vanilloid antagonists | Novartis AG (CH) | 2011-04-06 | — | — | EP | disclosed |