SCHEMBL16640701

SCHEMBL16640701

CC(C)(C)OC(=O)N(Cc1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
TSPO P30536 1/20 0.37
BCL2A1 Q16548 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18721166 0.93 KCNQ4 (0.43) BCL2A1
SCHEMBL31434524 0.93 AKT1 (0.44) NR1H4HDAC3HDAC1HDAC2NCOR2
SCHEMBL18011040 0.86 CYP3A4 (0.41)
SCHEMBL16640702 0.86 PHLPP2 (0.37)
SCHEMBL21418479 0.86 PHLPP2 (0.34) NR1H4HDAC3HDAC1HDAC2NCOR2
SCHEMBL4738587 0.84 TSHR (0.43)
SCHEMBL16682332 0.83 HDAC3 (0.51) HDAC3HDAC1HDAC2NCOR2
SCHEMBL7944783 0.83 GRM2 (0.44) HDAC3HDAC1HDAC2NCOR2
SCHEMBL16142413 0.82 L3MBTL1 (0.40) HDAC1HDAC2
SCHEMBL28836938 0.82 SSTR4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127655-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2018-05-10 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327744-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-20150119522-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2015-04-30 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed