SCHEMBL166411

SCHEMBL166411

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nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16059953 1.00
SCHEMBL109971 1.00
Acetaldehyde SCHEMBL1410064 0.90 GRIK1 (0.34)
Pyruvate SCHEMBL12003773 0.84 GRIK1 (0.31)
SCHEMBL14943775 0.83 TP53 (0.36)
SCHEMBL19615564 0.79 SLC22A6 (0.36)
SCHEMBL19615565 0.79 SLC22A6 (0.36)
SCHEMBL19615750 0.79 SLC22A6 (0.36)
SCHEMBL19615566 0.79 SLC22A6 (0.36)
2-Oxoisohexanoate SCHEMBL43491 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230045710-A1 AUTOMATED METHOD OF COMPUTATIONAL ENZYME IDENTIFICATION AND DESIGN ARZEDA CORPORATION 2023-02-09 US disclosed
US-11393556-B2 Automated method of computational enzyme identification and design ARZEDA CORPORATION (US) 2022-07-19 US disclosed
US-20190325984-A1 AUTOMATED METHOD OF COMPUTATIONAL ENZYME IDENTIFICATION AND DESIGN ARZEDA CORPORATION 2019-10-24 US disclosed
US-10246727-B2 Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives thereof ARZEDA CORP. (US) 2019-04-02 US disclosed
US-10025900-B2 Automated method of computational enzyme identification and design ARZEDA CORP. (US) 2018-07-17 US disclosed
US-20170275657-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS AND VALEROLACTONE AND DERIVATIVES THEREOF ARZEDA CORP. 2017-09-28 US disclosed
US-20170137855-A1 RECOMBINANT CELLS AND METHODS FOR NONPHOSPHORYLATIVE METABOLISM REGENTS OF THE UNIVERSITY OF MINNESOTA 2017-05-18 US disclosed
US-9523105-B2 Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives thereof ARZEDA CORPORATION (US) 2016-12-20 US disclosed
US-20160063177-A1 AUTOMATED METHOD OF COMPUTATIONAL ENZYME IDENTIFICATION AND DESIGN ARZEDA CORP. 2016-03-03 US disclosed
WO-2014144963-A1 AUTOMATED METHOD OF COMPUTATIONAL ENZYME IDENTIFICATION AND DESIGN ZANGHELLINI ALEXANDRE (US) 2014-09-18 WO disclosed
US-20130330779-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS AND VALEROLACTONE AND DERIVATIVES THEREOF ARZEDA CORPORATION 2013-12-12 US disclosed
EP-2611764-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF Arzeda Corp. (US) 2013-07-10 EP disclosed
WO-2012030860-A1 FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF ARZEDA CORP. (US) 2012-03-08 WO disclosed