SCHEMBL19615565

SCHEMBL19615565

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nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.36
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.32
SLC22A16 Q86VW1 1/20 0.32
CA2 P00918 1/20 0.32
OR51E2 Q9H255 1/20 0.32
GABRR1 P24046 2/20 0.31
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CACNB3 P54284 1/20 0.30
CACNA2D1 P54289 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19615750 1.00 SLC22A6 (0.36) SLC22A6TP53MAPTSLC22A16CA2
SCHEMBL19615564 1.00 SLC22A6 (0.36) SLC22A6TP53MAPTSLC22A16CA2
SCHEMBL19615566 1.00 SLC22A6 (0.36) SLC22A6TP53MAPTSLC22A16CA2
SCHEMBL17281366 0.82 GABRP (0.37) SLC22A6GABRR1LMNACACNB3CACNA2D1
SCHEMBL8292735 0.80 SLC22A6 (0.60) SLC22A6TP53MAPTGABRR1LMNA
SCHEMBL976030 0.80 SLC22A6 (0.60) SLC22A6TP53MAPTGABRR1LMNA
SCHEMBL976447 0.80 SLC22A6 (0.60) SLC22A6TP53MAPTGABRR1LMNA
SCHEMBL166411 0.79
SCHEMBL109971 0.79
SCHEMBL16059953 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458584-B1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR INVESTIGACION (ES) 2021-07-07 EP disclosed
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2020-06-16 US disclosed
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN TECHNICAL UNIVERSITY OF DARMSTADT (DE) 2019-06-27 US disclosed
EP-3458584-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN Consejo Superior De Investigaciones Científicas (ES) 2019-03-27 EP disclosed
WO-2017198717-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2017-11-23 WO disclosed
WO-2017198717-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2017-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN ALDOA, TALDO1, DERA SLC22A6 583/4885TP53 3562/4885MAPT 1406/4885
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein ALDOA, TALDO1, DERA SLC22A6 583/4885TP53 3562/4885MAPT 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.