Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669948 | 0.89 | ALOX5 (0.35) | ALOX5MAOBTNKSPARP1TNKS2 | |
| SCHEMBL21214774 | 0.88 | ALOX5 (0.46) | ALOX5TNKSPARP1TNKS2KDM4E | |
| SCHEMBL15851683 | 0.88 | ALOX5 (0.41) | ALOX5MAOBTNKSPARP1TNKS2 | |
| SCHEMBL24370077 | 0.87 | ALOX5 (0.43) | ALOX5TNKSKDM4EALDH1A1MAPT | |
| SCHEMBL24370266 | 0.87 | ALOX5 (0.43) | ALOX5TNKSKDM4EALDH1A1MAPT | |
| SCHEMBL21168539 | 0.87 | ALOX5 (0.45) | ALOX5TNKSPARP1TNKS2TP53 | |
| SCHEMBL24471775 | 0.87 | ALOX5 (0.45) | ALOX5TNKSPARP1TNKS2TP53 | |
| SCHEMBL16632552 | 0.87 | HDAC8 (0.39) | ALOX5MAOBTNKSKDM4ETP53 | |
| SCHEMBL17734631 | 0.87 | ALOX5 (0.40) | ALOX5TNKSMAPTGGPS1CRHR1 | |
| SCHEMBL15747067 | 0.87 | KDM4E (0.36) | ALOX5MAOBTNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |