Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16641986 | 0.84 | CA1 (0.64) | CA12CA1CA2CA9GAA | |
| SCHEMBL2985308 | 0.84 | CA1 (0.68) | CA12CA1CA2CA9GAA | |
| SCHEMBL16641979 | 0.83 | KMT2A (0.53) | CA12CA1CA2CA9GAA | |
| Hydrochloric Acid SCHEMBL10848274 | 0.83 | CA1 (0.67) | CA12CA1CA2CA9GAA | |
| SCHEMBL11764387 | 0.82 | CA12 (0.62) | CA12CA1CA2CA9GAA | |
| SCHEMBL15367453 | 0.80 | MAPT (0.50) | CA12CA1CA2CA9GAA | |
| SCHEMBL22624759 | 0.80 | KMT2A (0.50) | CA12CA1CA2CA9GAA | |
| SCHEMBL16645393 | 0.80 | CA12 (0.59) | CA12CA1CA2CA9GAA | |
| SCHEMBL16645403 | 0.80 | CYP2C9 (0.61) | CA12CA1CA2CA9GAA | |
| SCHEMBL29042293 | 0.79 | CA1 (0.52) | CA12CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | GRIN2A, GRIN1, GRIN2C | CA12 1006/4885CA1 455/4885CA2 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.