Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16645393 | 0.91 | CA12 (0.59) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL11764387 | 0.88 | CA12 (0.62) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL16641983 | 0.86 | ALB (0.58) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL16641984 | 0.84 | ALB (0.61) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL16641979 | 0.82 | KMT2A (0.53) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL15363559 | 0.82 | CYP2C9 (0.61) | CYP2C9CYP2C19CYP3A4CYP1A2PLA2G1B | |
| SCHEMBL2985308 | 0.80 | CA1 (0.68) | CYP2C9CYP2C19CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL16641986 | 0.80 | CA1 (0.64) | CYP2C9CYP2C19CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL16641981 | 0.80 | CA12 (0.63) | CA12CA1CA2CA9KMT2A | |
| Hydrochloric Acid SCHEMBL10848274 | 0.79 | CA1 (0.67) | CYP2C9CYP2C19CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | GRIN2A, GRIN1, GRIN2C | CYP2C9 4789/4885CYP2C19 4506/4885CYP3A4 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.