SCHEMBL1664368

SCHEMBL1664368

C#Cc1cnc2c(ccc3cccnc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.57
CCR8 P51685 5/20 0.57
CCR5 P51681 3/20 0.57
LMNA P02545 3/20 0.55
MAPT P10636 2/20 0.55
MMP2 P08253 2/20 0.55
TSHR P16473 2/20 0.55
KDM4E B2RXH2 1/20 0.55
GMNN O75496 1/20 0.55
TP53 P04637 1/20 0.55
HSP90AA1 P07900 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55
NFKB1 P19838 1/20 0.55
MMP8 P22894 1/20 0.55
THPO P40225 1/20 0.55
MTOR P42345 1/20 0.55
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420217 0.87 PARP1 (0.56) CCR1CCR8CCR5LMNAMAPT
SCHEMBL30492680 0.83 CCR1 (0.57) CCR1CCR8CCR5LMNAMAPT
SCHEMBL1994732 0.83 CCR1 (0.57) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL29635370 0.77 CCR1 (0.94) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL27885493 0.77 CCR1 (0.94) CCR1CCR8CCR5LMNAMAPT
SCHEMBL23954363 0.76 CCR1 (0.67) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL29354015 0.74 CCR1 (1.00) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL29367277 0.74 CCR1 (1.00) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL8312 0.74 CCR1 (1.00) CCR1CCR8CCR5LMNAMAPT
Phenanthroline SCHEMBL8845760 0.74 CCR1 (1.00) CCR1CCR8CCR5LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111423439-B Coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2022-11-18 CN claimed
CN-111423439-A Novel coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2020-07-17 CN claimed
CN-111423439-B Coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2022-11-18 CN disclosed
CN-111423439-B Coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2022-11-18 CN disclosed
CN-111423439-A Novel coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2020-07-17 CN disclosed
CN-111423439-A Novel coumarin conjugated heterocyclic fluorescent probe for detecting Fe (III) 南昌航空大学 2020-07-17 CN disclosed
US-7931975-B2 Electroluminescent device containing a flouranthene compound GLOBAL OLED TECHNOLOGY LLC (US) 2011-04-26 US disclosed
US-7931975-B2 Electroluminescent device containing a flouranthene compound GLOBAL OLED TECHNOLOGY LLC (US) 2011-04-26 US disclosed
US-7931975-B2 Electroluminescent device containing a flouranthene compound GLOBAL OLED TECHNOLOGY LLC (US) 2011-04-26 US disclosed
US-20100117519-A1 ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117519-A1 ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117519-A1 ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20030078416-A1 SUBSTITUTED PHENANTHROLINES REGENT OF THE UNIVERSITY OF CALIFORNIA, THE 2003-04-24 US disclosed
EP-0900220-A1 3- AND 3,8-SUBSTITUTED 1,10-PHENANTHROLINES AND THEIR USE IN ELECTRON AND ENERGY TRANSFER PROCESSES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-03-10 EP disclosed
WO-1997041122-A1 3- AND 3,8-SUBSTITUTED 1,10-PHENANTHROLINES AND THEIR USE IN ELECTRON AND ENERGY TRANSFER PROCESSES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078416-A1 SUBSTITUTED PHENANTHROLINES PAH, TET3, AHR CCR1 2636/4885CCR8 1706/4885CCR5 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.