Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 19/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632393 | 0.90 | HDAC3 (0.77) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16632298 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16632337 | 0.84 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL22874120 | 0.83 | HDAC3 (0.74) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL23518825 | 0.79 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16644402 | 0.78 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL17832679 | 0.77 | HDAC1 (0.56) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16636576 | 0.77 | HDAC1 (0.71) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16644400 | 0.73 | HDAC1 (0.54) | HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16644397 | 0.73 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054474-A1 | PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |