Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 20/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17958284 | 0.88 | GRIN1 (0.79) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645967 | 0.83 | GRIN2A (0.54) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645478 | 0.78 | GRIN1 (0.77) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645793 | 0.76 | GRIN1 (1.00) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645487 | 0.74 | GRIN1 (0.61) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645582 | 0.74 | GRIN1 (0.76) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645488 | 0.72 | GRIN1 (0.51) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL20403443 | 0.72 | GRIN1 (0.49) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16636818 | 0.72 | GRIN1 (0.73) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL17971469 | 0.72 | GRIN1 (0.69) | GRIN1GRIN2AGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052226-A1 | THIAZOLOPYRIMIDINONES AS MODULATORS OF NMDA RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-16 | — | — | WO | disclosed |