Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664562 | 0.94 | RAB9A (0.63) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1664967 | 0.93 | NPC1 (0.71) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1664970 | 0.90 | NPC1 (0.67) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1664961 | 0.89 | NPC1 (0.65) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1664965 | 0.84 | RAB9A (0.68) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1665272 | 0.83 | MAPT (0.61) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL1665013 | 0.82 | NPC1 (0.55) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1667241 | 0.81 | NPC1 (0.54) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1663562 | 0.79 | NPC1 (0.55) | RAB9ANPC1GFERKDM1ARCOR1 | |
| SCHEMBL1665017 | 0.79 | NPC1 (0.55) | RAB9ANPC1GFERKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |