⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL9457170 | 0.80 | ALDH1A1 (0.33) | — | |
| Water SCHEMBL1155773 | 0.75 | — | — | |
| Cyanamide SCHEMBL15863637 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL3507009 | 0.74 | — | — | |
| SCHEMBL1159492 | 0.72 | — | — | |
| SCHEMBL15863638 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL3394744 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11240538 | 0.72 | — | — | |
| SCHEMBL11495876 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL27922143 | 0.71 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165497-B1 | METHOD OF PREPARING GRANULAR N-ALKYL-AMMONIUM ACETONITRILE SALTS | BASF AG (DE) | 2004-02-25 | — | — | EP | claimed |
| CN-114630822-B | Biaryl dihydroorotate acid dehydrogenase inhibitors | 詹森生物科技公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20240158414-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. | 2024-05-16 | — | — | US | disclosed |
| EP-4041714-B1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-29 | — | — | US | disclosed |
| EP-4041714-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114630822-A | Biaryl dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-06-14 | — | — | CN | disclosed |
| US-11040976-B2 | Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-22 | — | — | US | disclosed |
| US-11040976-B2 | Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-22 | — | — | US | disclosed |
| WO-2021070132-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-1992021662-A1 | POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES | DOWELANCO (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5153316-A | Post and preemergence herbicides | DOWELANCO | 1992-10-06 | — | — | US | disclosed |
| US-4816526-A | Polyimide/polyetherimide resin blends | ICI AMERICAS INC. (US) | 1989-03-28 | — | — | US | disclosed |
| US-4757120-A | Polyimide/aromatic sulfone resin blends and prepegs coated therewith | ICI AMERICAS INC. (US) | 1988-07-12 | — | — | US | disclosed |
| US-4608382-A | ANTIINFLAMMABORY, ANTICOAGULANTS, ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1986-08-26 | — | — | US | disclosed |
| US-4584310-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1986-04-22 | — | — | US | disclosed |
| US-4461770-A | Mercaptoimidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1984-07-24 | — | — | US | disclosed |
| US-4025651-A | N-substituted-aminoacetamides used as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-05-24 | — | — | US | disclosed |
| US-3980777-A | INSECTICIDES, ACARICIDES, NEMATICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3966789-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-29 | — | — | US | disclosed |