⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024149 | 1.00 | — | — | |
| SCHEMBL20936934 | 1.00 | — | — | |
| SCHEMBL802509 | 1.00 | — | — | |
| SCHEMBL16376871 | 1.00 | — | — | |
| SCHEMBL12166822 | 0.85 | — | — | |
| SCHEMBL12237113 | 0.83 | MGAM (0.35) | — | |
| SCHEMBL23669404 | 0.83 | — | — | |
| SCHEMBL282940 | 0.83 | — | — | |
| SCHEMBL14455064 | 0.83 | — | — | |
| SCHEMBL17972920 | 0.81 | FUCA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |
| US-20150105390-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2015-04-16 | — | — | US | disclosed |