Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 19/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16266642 | 0.88 | HDAC3 (0.69) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL18742438 | 0.84 | HDAC3 (0.66) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL19710705 | 0.81 | HDAC6 (0.67) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL18769656 | 0.79 | HDAC3 (0.55) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL28067236 | 0.79 | HDAC3 (0.79) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL4729593 | 0.78 | HDAC3 (1.00) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29412232 | 0.78 | HDAC3 (1.00) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL17025843 | 0.77 | HDAC3 (0.67) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL19260835 | 0.77 | HDAC6 (0.74) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL4729915 | 0.76 | HDAC3 (1.00) | HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054197-A1 | HDAC INHIBITORS, ALONE OR IN COMBINATION WITH BTK INHIBITORS, FOR TREATING NON-HODGKIN'S LYMPHOMA | ACETYLON PHARMACEUTICALS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |