Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 6/20 | 0.88 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376701 | 0.93 | USP9X (1.00) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL16647263 | 0.93 | USP9X (1.00) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL17986430 | 0.93 | USP9X (1.00) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL18017556 | 0.93 | USP9X (0.75) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL16647236 | 0.89 | USP9X (0.82) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL23171163 | 0.86 | USP9X (0.76) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL18017557 | 0.86 | USP9X (0.86) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL18017555 | 0.86 | USP9X (0.86) | USP9XUSP24KMT2ACACNA1BAPBA1 | |
| SCHEMBL18017561 | 0.82 | USP9X (0.70) | USP9XUSP24KMT2AGAAKDM4E | |
| SCHEMBL18017565 | 0.78 | USP9X (0.73) | USP9XUSP24KMT2AGAAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868736-B2 | Deubiquitinase inhibitors and methods for use of the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-01-16 | — | — | US | disclosed |
| WO-2015054555-A1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-04-16 | — | — | WO | disclosed |