USP9X — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL882501	1.00	11/20
SCHEMBL1317669	1.00	11/20
SCHEMBL1317671	1.00	11/20
SCHEMBL1317674	1.00	11/20
SCHEMBL864885	0.85	11/20
SCHEMBL864886	0.85	11/20
SCHEMBL859666	0.81	11/20
SCHEMBL859667	0.81	11/20
SCHEMBL864393	0.81	11/20
SCHEMBL840599	0.79	11/20
SCHEMBL840600	0.79	11/20
SCHEMBL864115	0.78	11/20
SCHEMBL864116	0.78	11/20
SCHEMBL864117	0.78	11/20
SCHEMBL864118	0.78	11/20
SCHEMBL13349344	0.78	11/20
SCHEMBL10124900	0.78	11/20
SCHEMBL864194	0.75	11/20
SCHEMBL864195	0.75	11/20
SCHEMBL10124840	0.72	11/20

Clinical trials — most relevant to USP9X by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma	PHASE2	WITHDRAWN
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma	PHASE2	SUSPENDED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy	PHASE2	NOT_YET_RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
The Danish TURNER Cryopreservation Study	nan	RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1	nan	RECRUITING
New Signaling Pathway Targeting Systemic Lupus Erythematosus	nan	UNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
HCCBloodTest for Detection of Hepatocellular Carcinoma (HCC)	nan	COMPLETED
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.	nan	COMPLETED
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Chromosome 9 P Minus Syndrome	nan	RECRUITING
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit	nan	COMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
HRQoL and Financial Toxicity in Patients With VEXAS Syndrome	nan	RECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome	nan	RECRUITING
Genomic Analysis of Families With a History of Discordant Cancers	nan	RECRUITING
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a USP9X binder may also engage these)

Protein	Name	Similarity
P70398	—	1.000	P70398 →
O00507	—	0.988	O00507 →
Q8IWV8	—	0.985	Q8IWV8 →
Q7TPD0	—	0.984	Q7TPD0 →
Q86X10	—	0.983	Q86X10 →
Q96JJ3	—	0.981	Q96JJ3 →
Q8BHL5	—	0.980	Q8BHL5 →
Q5R644	—	0.980	Q5R644 →
O35841	—	0.979	O35841 →
Q68E01	—	0.979	Q68E01 →
Q9R1D7	—	0.979	Q9R1D7 →
Q7Z3J2	—	0.978	Q7Z3J2 →
Q5R8N4	—	0.978	Q5R8N4 →
P86410	—	0.977	P86410 →
Q8BWQ6	—	0.977	Q8BWQ6 →
Q924Z6	—	0.977	Q924Z6 →
Q8BQZ4	—	0.976	Q8BQZ4 →
Q08BT5	—	0.976	Q08BT5 →
Q5RE70	—	0.976	Q5RE70 →
Q5RCC1	—	0.975	Q5RCC1 →
Q6QI06	—	0.974	Q6QI06 →
Q9BZ29	—	0.973	Q9BZ29 →
XPO6	Exportin-6	0.973	landscape →
Q96PE3	—	0.973	Q96PE3 →
Q9P260	—	0.973	Q9P260 →
A4FUD6	—	0.973	A4FUD6 →
Q6P6Y1	—	0.973	Q6P6Y1 →
Q5XI83	—	0.973	Q5XI83 →
Q6DFZ1	—	0.972	Q6DFZ1 →
Q8IZD9	—	0.972	Q8IZD9 →