Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | ADA | P00813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639989 | 0.89 | HSP90B1 (0.33) | ADORA2ANT5EHSP90B1HINT1ADORA3 | |
| SCHEMBL20611239 | 0.88 | ADORA2A (0.36) | ADORA2ANT5EHSP90B1HINT1ADORA3 | |
| SCHEMBL16647574 | 0.88 | ADORA2A (0.34) | ADORA2ANT5EHSP90B1HINT1ADORA3 | |
| SCHEMBL16647595 | 0.86 | ADORA2A (0.39) | ADORA2ANT5EHSP90B1HINT1ADORA3 | |
| SCHEMBL17863693 | 0.85 | ADORA2A (0.38) | ADORA2ANT5EHSP90B1HINT1ADORA3 | |
| SCHEMBL15841096 | 0.85 | AHCY (0.33) | NT5EHSP90B1HINT1ADORA3ADORA1 | |
| SCHEMBL17359546 | 0.84 | — | — | |
| SCHEMBL15841033 | 0.84 | HSP90B1 (0.32) | HSP90B1HINT1ADORA3ADORA1ADORA2B | |
| SCHEMBL16644526 | 0.83 | HSP90B1 (0.32) | HSP90B1HINT1ADORA3ADORA1ADORA2B | |
| SCHEMBL16644433 | 0.82 | ADORA2A (0.32) | ADORA2AHSP90B1HINT1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054465-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |