Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4149865 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1665256 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1664499 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1665355 | 1.00 | — | — | |
| Water SCHEMBL29601630 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL206473 | 0.87 | — | — | |
| Water SCHEMBL5634857 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1414734 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1727377 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL717917 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-7923083-B2 | Recording medium, ink composition and recording method using the same | FUJIFILM CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| US-7736709-B2 | Recording medium and method for manufacturing recording medium | FUJIFILM CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| EP-1621359-B1 | Recording medium and its method of manufacture | FUJIFILM CORP (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-20070065606-A1 | Recording medium and method for manufacturing recording medium | FUJI PHOTO FILM CO., LTD. | 2007-03-22 | — | — | US | disclosed |
| EP-1621359-A2 | Recording medium, ink composition and recording method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-20050233097-A1 | Recording medium, ink composition and recording method using the same | FUJI PHOTO FILM CO., LTD. | 2005-10-20 | — | — | US | disclosed |
| WO-2005087499-A1 | RECORDING MEDIUM, INK COMPOSITION AND RECORDING METHOD USING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-22 | — | — | WO | disclosed |