Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16648084 | 0.94 | TRPA1 (0.71) | TRPA1 | |
| SCHEMBL16647736 | 0.91 | TRPA1 (0.68) | TRPA1 | |
| SCHEMBL16894196 | 0.83 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL16894159 | 0.81 | TRPA1 (0.84) | TRPA1 | |
| SCHEMBL16894201 | 0.77 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL17987061 | 0.75 | TRPA1 (0.62) | TRPA1 | |
| SCHEMBL16894252 | 0.75 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL16894185 | 0.75 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL16894184 | 0.75 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL16894128 | 0.74 | TRPA1 (0.61) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052264-A1 | SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-16 | — | — | WO | disclosed |