Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649782 | 0.87 | TUBB1 (0.50) | TUBB1LMNAHTTMAPK1RAB9A | |
| SCHEMBL3465192 | 0.82 | ALDH1A1 (0.49) | TUBB1LMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL3465918 | 0.79 | SMN1; SMN2 (0.48) | MAPK1ALDH1A1TSHRNFE2L2POLB | |
| SCHEMBL16877133 | 0.78 | TUBB1 (0.57) | TUBB1LMNAHTTMAPK1RAB9A | |
| SCHEMBL4163430 | 0.76 | ALDH1A1 (0.50) | RAB9AALDH1A1POLBKMT2A | |
| SCHEMBL14892303 | 0.76 | HTT (0.54) | LMNAHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL7531959 | 0.76 | ALDH1A1 (0.68) | TUBB1LMNAHTTMAPK1RAB9A | |
| SCHEMBL29400600 | 0.76 | ALDH1A1 (0.68) | TUBB1LMNAHTTMAPK1RAB9A | |
| SCHEMBL435689 | 0.76 | ALDH1A1 (0.68) | TUBB1LMNAHTTMAPK1RAB9A | |
| SCHEMBL18975197 | 0.73 | TUBB1 (0.56) | TUBB1LMNAHTTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |