Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240917 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1BLMLMNA | |
| SCHEMBL16649330 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3CHRM1BLMLMNA | |
| Trifluoroacetic Acid SCHEMBL2508865 | 0.93 | CHRM2 (0.39) | CHRM2CHRM3CHRM1BLMLMNA | |
| Trifluoroacetic Acid SCHEMBL2508867 | 0.93 | CHRM2 (0.39) | CHRM2CHRM3CHRM1BLMLMNA | |
| SCHEMBL8513388 | 0.84 | CTSS (0.44) | CHRM2CHRM3CHRM1BLMLMNA | |
| Bromide SCHEMBL8509268 | 0.83 | CTSS (0.43) | CHRM2CHRM3CHRM1BLMLMNA | |
| SCHEMBL2990935 | 0.80 | CHRM3 (0.67) | CHRM2CHRM3CHRM1BLMLMNA | |
| SCHEMBL13282704 | 0.79 | POLB (0.35) | CHRM2CHRM3THRBMEN1KMT2A | |
| SCHEMBL16649399 | 0.78 | CHRM3 (0.42) | CHRM2CHRM3CHRM1CYP2D6KMT2A | |
| SCHEMBL13240903 | 0.78 | CHRM3 (0.42) | CHRM2CHRM3CHRM1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | claimed |