Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649453 | 0.98 | S1PR1 (0.51) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL459629 | 0.90 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5LMNA | |
| SCHEMBL459976 | 0.88 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL16649017 | 0.83 | S1PR1 (0.65) | S1PR1S1PR4S1PR5 | |
| SCHEMBL16649221 | 0.82 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL16649300 | 0.81 | S1PR1 (0.68) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL16649369 | 0.80 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL16354018 | 0.78 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL16354038 | 0.76 | TP53 (0.47) | S1PR1S1PR3S1PR4S1PR5CYP2C8 | |
| SCHEMBL461235 | 0.75 | S1PR1 (0.47) | S1PR1S1PR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595969-B1 | Substituted 3-phenyl-1,2,4-oxadiazole compounds | BRISTOL MYERS SQUIBB CO (US) | 2015-04-22 | — | — | EP | claimed |