Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459343 | 0.91 | S1PR1 (0.63) | S1PR1 | |
| SCHEMBL16649274 | 0.83 | S1PR1 (0.68) | S1PR1TSHRHTTSMN1; SMN2ATM | |
| SCHEMBL16649210 | 0.83 | S1PR1 (0.72) | S1PR1TSHR | |
| SCHEMBL16649489 | 0.83 | S1PR1 (0.70) | S1PR1TSHR | |
| SCHEMBL16649339 | 0.82 | S1PR1 (0.74) | S1PR1 | |
| SCHEMBL16649531 | 0.79 | S1PR1 (0.81) | S1PR1 | |
| SCHEMBL16649017 | 0.76 | S1PR1 (0.65) | S1PR1HTTSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL16649292 | 0.76 | S1PR1 (0.79) | S1PR1 | |
| SCHEMBL16649147 | 0.76 | S1PR1 (0.68) | S1PR1 | |
| SCHEMBL16649094 | 0.76 | S1PR1 (0.66) | S1PR1TSHRHTTATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595969-B1 | Substituted 3-phenyl-1,2,4-oxadiazole compounds | BRISTOL MYERS SQUIBB CO (US) | 2015-04-22 | — | — | EP | claimed |