SCHEMBL16650820

SCHEMBL16650820

COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)NCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.58
TP53 P04637 1/20 0.58
GLA P06280 1/20 0.58
PPARA Q07869 5/20 0.53
PPARG P37231 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
BRD4 O60885 1/20 0.50
TSHR P16473 1/20 0.50
BLM P54132 1/20 0.50
CYP2C19 P33261 1/20 0.49
HSD17B10 Q99714 2/20 0.48
POLB P06746 1/20 0.48
LMNA P02545 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21817011 0.86 HPGD (0.64) HPGDTP53GLAL3MBTL1ALDH1A1
SCHEMBL16658358 0.85 HTT (0.50) HPGDTP53GLAALDH1A1CYP1A2
SCHEMBL29404584 0.85 CA1 (0.50) HPGDTP53GLAPPARAPPARG
SCHEMBL21816957 0.85 CA1 (0.50) HPGDTP53GLAPPARAPPARG
SCHEMBL16679886 0.84 HTT (0.49) HPGDPPARGALDH1A1CYP3A4KMT2A
SCHEMBL20145425 0.83 CA1 (0.52) HPGDTP53GLAALDH1A1CYP1A2
SCHEMBL18641941 0.81 HPGD (0.60) HPGDTP53GLAALDH1A1MEN1
SCHEMBL29617726 0.81 HPGD (0.60) HPGDTP53GLAALDH1A1MEN1
SCHEMBL29617693 0.80 HPGD (0.55) HPGDTP53GLAALDH1A1KMT2A
SCHEMBL18641948 0.80 HPGD (0.55) HPGDTP53GLAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134364-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2025-07-30 EP disclosed
US-20240182490-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2024-06-06 US disclosed
US-11884680-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2024-01-30 US disclosed
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
US-20220315601-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2022-10-06 US disclosed
EP-3640241-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-09-28 EP disclosed
EP-3532059-B1 BROMODOMAIN AND EXTRA-TERMINAL PROTEIN INHIBITOR COMBINATION THERAPY CELGENE QUANTICEL RES INC (US) 2022-01-26 EP disclosed
CN-108558889-B Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2021-11-05 CN disclosed
US-10941160-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-03-09 US disclosed
US-9115114-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-08-25 US disclosed
US-9115114-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-08-25 US disclosed
US-20150183784-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-07-02 US disclosed
US-20150183784-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-07-02 US disclosed
US-9034900-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-05-19 US disclosed
US-9034900-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-05-19 US disclosed
US-20150111885-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-04-23 US disclosed
WO-2015058160-A1 BROMODOMAIN INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2015-04-23 WO disclosed
WO-2015058160-A1 BROMODOMAIN INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2015-04-23 WO disclosed
US-20150111885-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2015-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182490-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885
US-20220315601-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885
US-20150111885-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885
US-10941160-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885
US-20150183784-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885
US-11884680-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 HPGD 1266/4885TP53 102/4885GLA 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.