Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL9181910 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL275423 | 0.91 | — | — | |
| Succinic Acid SCHEMBL21958272 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL10785057 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL2222367 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL8328761 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL21958270 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL22471655 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL1462992 | 0.91 | — | — | |
| Succinic Acid SCHEMBL165196 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430159-A | High-refractive-index precursor liquid, preparation method and application thereof | 西安思摩威新材料有限公司 | 2024-01-23 | — | — | CN | claimed |
| EP-1305273-B1 | METHOD FOR OXIDISING HYDROCARBONS, ALCOHOLS AND/OR KETONES | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2005-04-27 | — | — | EP | claimed |
| US-6762319-B1 | Hydrocarbon, alcohol and/or ketone oxidation method | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2004-07-13 | — | — | US | claimed |
| EP-1165481-B1 | PROCESS FOR THE OXIDATION OF CYCLOALKANES, CYCLOALCOHOLS AND/OR CYCLOKETONES | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2003-09-17 | — | — | EP | claimed |
| EP-0870751-B1 | Process for the oxidation of hydrocarbons, alcohols and/or ketons | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2003-06-18 | — | — | EP | claimed |
| CN-117430159-A | High-refractive-index precursor liquid, preparation method and application thereof | 西安思摩威新材料有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-116509894-A | Zirconium ball water flies device suitable for industrial production of hard mineral medicine | 长春中医药大学 | 2023-08-01 | — | — | CN | disclosed |
| US-7923083-B2 | Recording medium, ink composition and recording method using the same | FUJIFILM CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| US-7705179-B2 | Method for oxidising hydrocarbons, alcohols and/or ketones | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2010-04-27 | — | — | US | disclosed |
| EP-1621359-B1 | Recording medium and its method of manufacture | FUJIFILM CORP (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-7223453-B2 | Ink jet recording medium and ink jet recording method | FUJIFILM CORPORATION (JP) | 2007-05-29 | — | — | US | disclosed |
| EP-1621359-A2 | Recording medium, ink composition and recording method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-0439503-A1 | COATING COMPOSITIONS AND EMULSIONS | Brown, Nicholas (GB) | 1991-08-07 | — | — | EP | disclosed |
| WO-1990004616-A2 | COATING COMPOSITIONS AND EMULSIONS | BROWN NICHOLAS (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365335-A2 | Coating compositions and emulsions | Brown, Nicholas (GB) | 1990-04-25 | — | — | EP | disclosed |
| EP-0246761-A1 | Preparation of high purity zirconia and zirconia mixtures from zirconium carbonate | Corning Glass Works (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0089425-B1 | METHOD FOR THE PREPARATION OF INTEGRAL SHAPED REPLICATIONS OF SHAPED, POROUS AND DISSOLVABLE MATERIALS FOR USE AS ADSORBENTS IN FIXED BED ADSORPTION PROCESSES | UOP INC. (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0089425-A1 | Method for the preparation of integral shaped replications of shaped, porous and dissolvable materials for use as adsorbents in fixed bed adsorption processes | UOP INC. (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4329260-A | CARBONACEOUS PYROPLYMER | UOP INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4220585-A | Drilling fluid additives | DRESSER INDUSTRIES, INC. (US) | 1980-09-02 | — | — | US | disclosed |