Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665270 | 0.92 | MGLL (0.43) | MGLLMAPK1HPGDMAPK8MAPK10 | |
| SCHEMBL1664246 | 0.84 | SYK (0.44) | MGLLMAPK1SYKMAPK8MAPK10 | |
| SCHEMBL8771617 | 0.84 | MGLL (0.46) | MGLLMBTD1TP53BP1L3MBTL4L3MBTL3 | |
| SCHEMBL6126221 | 0.84 | MGLL (0.41) | MGLLMAPK1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL1664251 | 0.81 | MAOB (0.45) | MAPK1HPGDMAPK8MAPK10MAPK14 | |
| SCHEMBL1664474 | 0.81 | TNIK (0.46) | L3MBTL1HPGDMAPK8MAPK10MAPK14 | |
| SCHEMBL8773474 | 0.81 | NAMPT (0.47) | MGLLMAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL1665009 | 0.80 | TNIK (0.44) | MGLLMAPK1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL1663875 | 0.80 | TDP1 (0.47) | MAPK1L3MBTL1HPGDMAPK8MAPK10 | |
| SCHEMBL1663342 | 0.80 | MAOB (0.52) | MGLLHPGDMAPK8MAPK10MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |