Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165068 | 0.97 | — | — | |
| SCHEMBL27843059 | 0.97 | LMNA (0.50) | — | |
| Hydrochloric Acid SCHEMBL4562672 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15476008 | 0.97 | — | — | |
| SCHEMBL28192357 | 0.94 | — | — | |
| Methylamine SCHEMBL27463181 | 0.92 | LMNA (0.52) | — | |
| Pyrimidine SCHEMBL29088473 | 0.81 | LMNA (0.38) | — | |
| SCHEMBL15513446 | 0.78 | LMNA (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL22573064 | 0.76 | HRH4 (0.37) | — | |
| Acetophenone SCHEMBL28037682 | 0.71 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10315999-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180282285-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | CORTEVA AGRISCIENCE LLC | 2018-10-04 | — | — | US | disclosed |
| US-9988356-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2018-06-05 | — | — | US | disclosed |
| CN-105636444-B | Process for preparing pesticidal compounds | 美国陶氏益农公司 | 2018-04-27 | — | — | CN | disclosed |
| US-20180016238-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2018-01-18 | — | — | US | disclosed |
| US-9796682-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-9670164-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2017-06-06 | — | — | US | disclosed |
| US-20170081288-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2017-03-23 | — | — | US | disclosed |
| US-9540342-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2017-01-10 | — | — | US | disclosed |
| EP-3057425-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | Dow AgroSciences LLC (US) | 2016-08-24 | — | — | EP | disclosed |
| US-20160152594-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | CORTEVA AGRISCIENCE LLC | 2016-06-02 | — | — | US | disclosed |
| CN-105636444-A | Process for preparing pesticidal compounds | DOW AGROSCIENCES LLC | 2016-06-01 | — | — | CN | disclosed |
| US-9255082-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2016-02-09 | — | — | US | disclosed |
| US-20150252016-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | CORTEVA AGRISCIENCE LLC | 2015-09-10 | — | — | US | disclosed |
| US-9102655-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150112076-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| WO-2015058024-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2015-04-23 | — | — | WO | disclosed |