SCHEMBL16653249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL290442	0.89	CYP1A2 (0.49)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL16653306	0.86	CYP3A4 (0.50)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL16660133	0.82	CYP1A2 (0.46)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL15047295	0.81	CYP1A2 (0.52)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL290486	0.81	CYP1A2 (0.47)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL16660151	0.79	CYP1A2 (0.43)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL17629275	0.79	CYP1A2 (0.47)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL290376	0.79	CYP1A2 (0.49)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL13048198	0.79	CYP1A2 (0.45)	CYP1A2CYP3A4CYP2C19LMNAKDM4E
	SCHEMBL13048421	0.78	CYP1A2 (0.46)	CYP1A2CYP3A4CYP2C19LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.