⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330188 | 1.00 | — | — | |
| SCHEMBL7459049 | 0.97 | — | — | |
| SCHEMBL1697434 | 0.94 | — | — | |
| SCHEMBL3857933 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL1547638 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL23072256 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL31611656 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL12396667 | 0.77 | AKR1B1 (0.37) | — | |
| SCHEMBL15329241 | 0.73 | AKR1B1 (0.30) | — | |
| SCHEMBL9147251 | 0.73 | AKR1B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727586-A1 | ANTI-CD5 ANTIBODIES AND THEIR USES | Synthis Therapeutics, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4674440-A2 | SITE-SPECIFIC ANTIBODY-DRUG GLYCOCONJUGATES AND METHODS | University of Georgia Research Foundation, Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-3129402-B1 | SITE-SPECIFIC ANTIBODY-DRUG GLYCOCONJUGATES AND METHODS | UNIV GEORGIA (US) | 2025-11-26 | — | — | EP | disclosed |
| US-20250222124-A1 | PROTEIN CONJUGATES WITH MULTIPLE PAYLOADS AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2025-07-10 | — | — | US | disclosed |
| US-12281174-B2 | High-affinity anti-MERTK antibodies and uses thereof | INSPIRNA, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-119735688-A | High-affinity anti-MERTK antibodies and uses thereof | 茵思博纳公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119488607-A | Antibody-ALK 5 inhibitor conjugate and application thereof | 辛瑟斯治疗股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024258967-A1 | ANTI-CD5 ANTIBODIES AND THEIR USES | SYNTHIS THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-12162942-B2 | Anti-MERTK agonistic antibodies and uses thereof | THE ROCKEFELLER UNIVERSITY (US) | 2024-12-10 | — | — | US | disclosed |
| CN-112601522-B | Antibody-ALK 5 inhibitor conjugate and application thereof | 辛瑟斯治疗股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20160250347-A1 | MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF | SYNAFFIX B.V. (NL) | 2016-09-01 | — | — | US | disclosed |
| EP-3057618-A1 | GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION | SynAffix B.V. (NL) | 2016-08-24 | — | — | EP | disclosed |
| EP-3058083-A1 | MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF | SynAffix B.V. (NL) | 2016-08-24 | — | — | EP | disclosed |
| US-20160235861-A1 | GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION | SynAffix. B.V. (NL) | 2016-08-18 | — | — | US | disclosed |
| EP-2935608-A1 | MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF | SynAffix B.V. (NL) | 2015-10-28 | — | — | EP | disclosed |
| EP-2935611-A1 | GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION | SynAffix B.V. (NL) | 2015-10-28 | — | — | EP | disclosed |
| WO-2015057066-A1 | GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION | SYNAFFIX B.V. (NL) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015057064-A1 | MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF | SYNAFFIX B.V. (NL) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015057063-A1 | MODIFIED GLYCOPROTEIN, PROTEIN-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF | SYNAFFIX B.V. (NL) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015057065-A1 | GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION | SYNAFFIX B.V. (NL) | 2015-04-23 | — | — | WO | disclosed |