Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666087 | 0.81 | HTT (0.42) | LMNAHTTMAPTPOLBMEN1 | |
| SCHEMBL30316885 | 0.77 | POLB (0.42) | LMNAHTTMAPTPOLBKMT2A | |
| SCHEMBL16666097 | 0.74 | HTT (0.37) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL16653795 | 0.67 | — | — | |
| SCHEMBL16654038 | 0.67 | — | — | |
| SCHEMBL16653794 | 0.67 | — | — | |
| SCHEMBL493054 | 0.66 | MAPT (0.44) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL1559736 | 0.64 | CYP1A2 (0.37) | LMNAHTTMAPTPOLBMEN1 | |
| SCHEMBL38665481 | 0.64 | CYP1A2 (0.44) | LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL6826580 | 0.63 | MAPT (0.52) | LMNAHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015055764-A1 | 3-METHANIMIDAMID-PYRIDINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-23 | — | — | WO | disclosed |