Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299423 | 0.87 | ALDH1A1 (0.50) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL29502892 | 0.87 | ALDH1A1 (0.50) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL6584963 | 0.85 | TSHR (0.51) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL21835757 | 0.81 | ALDH1A1 (0.46) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL30977610 | 0.81 | ATM (0.55) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL692339 | 0.81 | ATM (0.55) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL4323918 | 0.81 | LMNA (0.49) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL30720021 | 0.80 | GPR35 (0.51) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL19554275 | 0.80 | MAPT (0.58) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL13807644 | 0.80 | MAPT (0.49) | MAPTLMNAMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150277-A1 | Covalent PPARG inverse-agonists | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-09 | — | — | US | disclosed |
| US-20040248877-A1 | Polycyclic diazodioxide-based Bcl-2 protein antagonists and use thereof | RICERCA BIOSCIENCES, LLC. | 2004-12-09 | — | — | US | disclosed |
| WO-2004099162-A1 | POLYCYCLIC DIAZODIOXIDE-BASED BCL-2 PROTEIN ANTAGONIST | RICERCA BIOSCIENCES, LLC. (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150277-A1 | Covalent PPARG inverse-agonists | PPARG, PPARD, PPARA | MAPT 4826/4885LMNA 716/4885MEN1 4688/4885 |
| US-20040248877-A1 | Polycyclic diazodioxide-based Bcl-2 protein antagonists and use thereof | BCL2L2, BCL2, BCL2L1 | MAPT 4829/4885LMNA 2452/4885MEN1 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.