Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654257 | 0.91 | RORC (0.76) | RORC | |
| SCHEMBL16652128 | 0.87 | RORC (1.00) | RORC | |
| SCHEMBL16651664 | 0.86 | RORC (1.00) | RORC | |
| SCHEMBL16652065 | 0.84 | RORC (1.00) | RORC | |
| SCHEMBL16662036 | 0.82 | RORC (0.87) | RORC | |
| SCHEMBL16662008 | 0.82 | RORC (0.92) | RORC | |
| SCHEMBL16662007 | 0.82 | RORC (0.86) | RORC | |
| SCHEMBL16652358 | 0.82 | RORC (1.00) | RORC | |
| SCHEMBL16652125 | 0.82 | RORC (1.00) | RORC | |
| SCHEMBL16652272 | 0.81 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057422-A1 | QUINOLINYL MODULATORS OF ROR(GAMMA)T | Janssen Pharmaceutica NV (BE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057626-A1 | QUINOLINYL MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |